RESEARCH THEME 02

Smart Biochip Engineering

Designing intelligent miniaturized systems for advanced biological applications.

Overview

Original concept-stage microfluidic CAD chip design with four channels and microwell arrays

Smart Biochip Engineering at SIBES explores how microchannel architecture, miniaturized reactions, integrated sensing and computational approaches can enable precise microscale biological analysis.

Research interests span computer-aided design, CFD and multiphysics simulation, device materials and fabrication strategies, fluid transport and mixing, optical or electrochemical detection, and automated device control.

Original CAD renderings are presented as design concepts; they are not representations of fabricated or validated diagnostic devices.

Design · Simulate · Fabricate · Integrate · Apply

01DesignMicrochannel layouts, arrays and fluidic architectures
02SimulateCFD, mixing, transport, pressure and mass transfer
03FabricateMaterial selection, 3D printing, micromachining and assembly
04Integrate & testFluid handling, sensors, electronics and experiments
05ApplicationsDiagnostics, biosensing and bioanalysis

Research focus areas

Microfluidic design

Microfluidic design

Chip architectures, multiple inlet and outlet configurations, reaction chambers and engineered microstructures.

CFD and optimization

CFD and optimization

Evaluating microchannel geometries, multiphase flow and concentration distributions.

Fabrication strategies

Fabrication strategies

Investigating material and fabrication routes, bonding, module assembly and testing.

Intelligent fluid handling

Intelligent fluid handling

Exploring computer-vision-assisted control, pumps, valves and data-informed fluidic operation.

Integrated sensing

Integrated sensing

Exploring interfaces for electrochemical, optical and other analytical readouts.

Potential applications

Potential applications

Molecular diagnostics, biosensing, miniaturized bioprocessing and biochemical analysis.